IREM1 抗体 (Internal Region)
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- 抗原 See all IREM1 抗体
- IREM1 (Immune Receptor Expressed On Myeloid Cells 1 (IREM1))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IREM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- CLM-1 Antibody detects endogenous levels of total CLM-1.
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CLM-1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product IREM1 Primary Antibody
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anti-Immune Receptor Expressed On Myeloid Cells 1 (IREM1) (AA 45-310) antibody
IREM1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Immune Receptor Expressed On Myeloid Cells 1 (IREM1) (Internal Region) antibodyIREM1 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Immune Receptor Expressed On Myeloid Cells 1 (IREM1) (AA 56-84), (N-Term) antibodyIREM1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22264 unconjugated
anti-Immune Receptor Expressed On Myeloid Cells 1 (IREM1) (AA 63-92), (N-Term) antibodyIREM1 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Immune Receptor Expressed On Myeloid Cells 1 (IREM1) (Internal Region) antibodyIREM1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immune Receptor Expressed On Myeloid Cells 1 (IREM1) (AA 23-150) antibodyIREM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- IREM1 (Immune Receptor Expressed On Myeloid Cells 1 (IREM1))
- 别名
- CD300LF (IREM1 产品)
- 别名
- CLIM1 antibody, CLM-1 antibody, CLM1 antibody, Digr2 antibody, F730004D16Rik antibody, IREM1 antibody, IgSF13 antibody, LMIR3 antibody, Pigr3 antibody, CD300f antibody, RGD1309733 antibody, IREM-1 antibody, NKIR antibody, CD300 molecule like family member F antibody, Cd300 molecule-like family member F antibody, CD300 molecule like family member f antibody, Cd300lf antibody, CD300LF antibody
- 背景
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Description: Acts as an inhibitory receptor for myeloid cells and mast cells (PubMed:15549731). Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition, recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis (By similarity). Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide and sphingomyelin which act as ligands (PubMed:24035150). May act as a coreceptor for interleukin 4 (IL-4). Associates with and regulates IL-4 receptor alpha-mediated responses by augmenting IL-4- and IL-13-induced signaling (By similarity). Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 and TRIF through activation of PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:22043923). Inhibits osteoclast formation. Induces macrophage cell death upon engagement (By similarity).
Gene: CD300LF
- 分子量
- 30 kDa
- 基因ID
- 146722
- UniProt
- Q8TDQ1
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