TSEN54 抗体 (Internal Region)
Quick Overview for TSEN54 抗体 (Internal Region) (ABIN6258653)
抗原
See all TSEN54 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- TSEN54 Antibody detects endogenous levels of total TSEN54.
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预测反应
- Bovine
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human TSEN54, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-tRNA Splicing Endonuclease 54 (TSEN54) antibody
TSEN54 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-tRNA Splicing Endonuclease 54 (TSEN54) (AA 427-525) antibodyTSEN54 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-tRNA Splicing Endonuclease 54 (TSEN54) (AA 1-300) antibodyTSEN54 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))
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别名
- TSEN54
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背景
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Description: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
Gene: TSEN54
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分子量
- 59 kDa
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基因ID
- 283989
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UniProt
- Q7Z6J9
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途径
- Synaptic Membrane
抗原
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