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RHOB 抗体 (Internal Region)

This anti-RHOB antibody is a 兔 多克隆 antibody detecting RHOB in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6258639
发货至: 中国

Quick Overview for RHOB 抗体 (Internal Region) (ABIN6258639)

抗原

See all RHOB 抗体
RHOB (Ras Homolog Gene Family, Member B (RHOB))

适用

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  • 17
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  • 2
  • 2
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  • 1
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人, 小鼠, 大鼠

宿主

  • 43
  • 2
  • 1

克隆类型

  • 44
  • 2
多克隆

标记

  • 22
  • 3
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  • 1
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  • 1
  • 1
  • 1
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  • 1
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  • 1
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This RHOB antibody is un-conjugated

应用范围

  • 19
  • 13
  • 13
  • 13
  • 7
  • 6
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    特异性

    RHOB Antibody detects endogenous levels of total RHOB.

    预测反应

    Bovine,Horse,Sheep,Dog,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human RHOB, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    RHOB (Ras Homolog Gene Family, Member B (RHOB))

    别名

    RHOB

    背景

    Description: Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

    Gene: RHOB

    分子量

    22 kDa

    基因ID

    388

    UniProt

    P62745
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