CD177 抗体 (Internal Region)
Quick Overview for CD177 抗体 (Internal Region) (ABIN6258621)
抗原
See all CD177 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- CD177 Antibody detects endogenous levels of total CD177.
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CD177, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-CD177 Molecule (CD177) (AA 521-650) antibody
CD177 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD177 Molecule (CD177) (AA 21-120) antibodyCD177 适用: 人 WB, IP, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4C4 unconjugated
anti-CD177 Molecule (CD177) antibodyCD177 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD177 Molecule (CD177) (AA 22-161) antibodyCD177 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 2F2C1 unconjugated
anti-CD177 Molecule (CD177) (AA 193-468) antibodyCD177 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD177 Molecule (CD177) (AA 133-301) antibodyCD177 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD177 Molecule (CD177) (AA 22-321) antibodyCD177 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD177 Molecule (CD177) antibody (FITC)CD177 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-166 FITC
anti-CD177 Molecule (CD177) antibody (PE)CD177 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-166 PE
anti-CD177 Molecule (CD177) antibodyCD177 适用: 人 WB, IP, IHC (p), EIA 宿主: 小鼠 Monoclonal 4C4 unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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有效期
- 12 months
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- CD177 (CD177 Molecule (CD177))
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别名
- CD177
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背景
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Description: In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18, mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production (PubMed:21193407). In addition, by preventing beta-2 integrin internalization and attenuating chemokine signaling favors adhesion over migration (PubMed:28807980). Heterophilic interaction with PECAM1 on endothelial cells plays a role in neutrophil transendothelial migration in vitro (PubMed:17580308). However, appears to be dispensable for neutrophil recruitment caused by bacterial infection in vivo (PubMed:23461681). Acts as a receptor for the mature form of protease PRTN3 allowing its display at the cell surface of neutrophils (PubMed:17244676, PubMed:18462208). By displaying PRTN3 at the neutrophil cell surface, may play a role in enhancing endothelial cell junctional integrity and thus vascular integrity during neutrophil diapedesis (PubMed:23202369).
Gene: CD177
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分子量
- ?46 kDa
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基因ID
- 57126
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UniProt
- Q8N6Q3
抗原
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