USP44 抗体 (Internal Region)
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Quick Overview for USP44 抗体 (Internal Region) (ABIN6258564)
抗原
See all USP44 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- USP44 Antibody detects endogenous levels of total USP44.
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预测反应
- Bovine,Horse,Sheep,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human USP44, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Ubiquitin Specific Peptidase 44 (USP44) (Internal Region) antibody
USP44 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 44 (USP44) (N-Term) antibodyUSP44 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 斑马鱼, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 44 (USP44) (AA 211-260) antibodyUSP44 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- USP44 (Ubiquitin Specific Peptidase 44 (USP44))
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别名
- USP44
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背景
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Description: Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex (also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B (H2BK120ub1) ubiquitination.
Gene: USP44
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分子量
- 81 kDa
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基因ID
- 84101
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UniProt
- Q9H0E7
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途径
- M Phase
抗原
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