Usp30 抗体 (N-Term)
Quick Overview for Usp30 抗体 (N-Term) (ABIN6258562)
抗原
See all Usp30 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- USP30 Antibody detects endogenous levels of total USP30.
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预测反应
- Pig,Bovine,Horse,Sheep,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human USP30, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Ubiquitin Specific Peptidase 30 (Usp30) (Middle Region) antibody
Usp30 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 30 (Usp30) (AA 57-390) antibodyUsp30 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 30 (Usp30) (AA 141-190) antibodyUsp30 适用: 人, 小鼠, 大鼠, 犬, 猴, Cow, 豚鼠, 马, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 30 (Usp30) (N-Term) antibodyUsp30 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 30 (Usp30) (N-Term) antibodyUsp30 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Usp30 (Ubiquitin Specific Peptidase 30 (Usp30))
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别名
- USP30
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背景
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Description: Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin's ability to drive mitophagy (PubMed:18287522, PubMed:24896179, PubMed:25527291, PubMed:25621951). Preferentially cleaves 'Lys-6'- and 'Lys-11'-linked polyubiquitin chains, 2 types of linkage that participate to mitophagic signaling (PubMed:25621951). Does not cleave efficiently polyubiquitin phosphorylated at 'Ser-65' (PubMed:25527291). Acts as negative regulator of mitochondrial fusion by mediating deubiquitination of MFN1 and MFN2 (By similarity).
Gene: USP30
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分子量
- 60 kDa
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基因ID
- 84749
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UniProt
- Q70CQ3
抗原
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