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Nesprin3 抗体 (N-Term)

This anti-Nesprin3 antibody is a 兔 多克隆 antibody detecting Nesprin3 in WB, ELISA, IF 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6258552
发货至: 中国

Quick Overview for Nesprin3 抗体 (N-Term) (ABIN6258552)

抗原

See all Nesprin3 (C14orf49) 抗体
Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

适用

  • 45
  • 40
  • 16
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 45
  • 1

克隆类型

  • 42
  • 4
多克隆

标记

  • 21
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Nesprin3 antibody is un-conjugated

应用范围

  • 39
  • 13
  • 13
  • 13
  • 9
  • 8
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    C14orf49 Antibody detects endogenous levels of total C14orf49.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human C14orf49, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

    别名

    SYNE3

    背景

    Description: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.

    Gene: SYNE3

    分子量

    130 kDa

    基因ID

    161176

    UniProt

    Q6ZMZ3

    途径

    Maintenance of Protein Location
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