COQ8A 抗体 (Internal Region)
Our Local Distributor
北京 101111
Quick Overview for COQ8A 抗体 (Internal Region) (ABIN6258497)
抗原
See all COQ8A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
原理
- ADCK3 Antibody
-
特异性
- ADCK3 Antibody detects endogenous levels of total ADCK3
-
预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human ADCK3, corresponding to a region within the internal amino acids.
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- COQ8A (Coenzyme Q8A (COQ8A))
-
别名
- ADCK3
-
背景
-
Description: Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:25498144, PubMed:21296186, PubMed:25540914, PubMed:27499294). Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:25498144, PubMed:27499294). Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (PubMed:25498144, PubMed:27499294). Shows an unusual selectivity for binding ADP over ATP (PubMed:25498144).
Gene: COQ8A
-
分子量
- 50 kDa
-
基因ID
- 56997
-
UniProt
- Q8NI60
抗原
-