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Fibrinogen beta Chain 抗体 (C-Term)

This anti-Fibrinogen beta Chain antibody is a 兔 多克隆 antibody detecting Fibrinogen beta Chain in WB, IHC, ELISA, ICC 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN6258456
发货至: 中国

Quick Overview for Fibrinogen beta Chain 抗体 (C-Term) (ABIN6258456)

抗原

See all Fibrinogen beta Chain (FGB) 抗体
Fibrinogen beta Chain (FGB)

适用

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人, 小鼠

宿主

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克隆类型

  • 71
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多克隆

标记

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This Fibrinogen beta Chain antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    特异性

    FGB Antibody detects endogenous levels of total FGB.

    预测反应

    Zebrafish,Bovine,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human FGB, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    Fibrinogen beta Chain (FGB)

    别名

    FGB

    背景

    Description: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

    Gene: FGB

    分子量

    56 kDa

    基因ID

    2244

    UniProt

    P02675
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