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Chp2 抗体 (Internal Region)

This anti-Chp2 antibody is a 兔 多克隆 antibody detecting Chp2 in WB, ELISA, IF, ICC 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6258442
发货至: 中国

Quick Overview for Chp2 抗体 (Internal Region) (ABIN6258442)

抗原

Chp2

适用

  • 26
  • 11
  • 11
  • 1
人, 小鼠, 大鼠

宿主

  • 14
  • 12

克隆类型

  • 14
  • 12
多克隆

标记

  • 11
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Chp2 antibody is un-conjugated

应用范围

  • 19
  • 13
  • 5
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC)
  • 抗原表位

    • 3
    • 2
    • 1
    • 1
    • 1
    Internal Region

    特异性

    CHP2 Antibody detects endogenous levels of total CHP2.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human CHP2, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    Chp2

    背景

    Description: Functions as an integral cofactor in cell  pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing  pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.

    Gene: CHP2

    分子量

    22 kDa

    基因ID

    63928

    UniProt

    O43745
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