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YWHAB 抗体 (C-Term)

This anti-YWHAB antibody is a 兔 多克隆 antibody detecting YWHAB in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6258358
发货至: 中国

Quick Overview for YWHAB 抗体 (C-Term) (ABIN6258358)

抗原

See all YWHAB 抗体
YWHAB (14-3-3 alpha + beta (YWHAB))

适用

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人, 小鼠, 大鼠

宿主

  • 77
  • 6
  • 1

克隆类型

  • 65
  • 19
多克隆

标记

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This YWHAB antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
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    C-Term

    特异性

    14-3-3 beta Antibody detects endogenous levels of total 14-3-3 beta.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human 14-3-3 beta, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    YWHAB (14-3-3 alpha + beta (YWHAB))

    别名

    YWHAB

    背景

    Description: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.

    Gene: YWHAB

    分子量

    28 kDa

    基因ID

    7529

    UniProt

    P31946

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location
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