USP11 抗体 (Internal Region)
Quick Overview for USP11 抗体 (Internal Region) (ABIN6258345)
抗原
See all USP11 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
特异性
- USP11 Antibody detects endogenous levels of total USP11.
-
预测反应
- Rabbit
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human USP11, corresponding to a region within the internal amino acids.
-
亚型
- IgG
-
-
anti-Ubiquitin Specific Peptidase 11 (USP11) (AA 201-300) antibody
USP11 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8G5 unconjugated
anti-Ubiquitin Specific Peptidase 11 (USP11) (N-Term) antibodyUSP11 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 11 (USP11) (AA 32-300), (N-Term) antibodyUSP11 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1220CT620-193-189 unconjugated
anti-Ubiquitin Specific Peptidase 11 (USP11) antibodyUSP11 适用: 人 WB 宿主: 小鼠 Monoclonal 2C9 unconjugated
anti-Ubiquitin Specific Peptidase 11 (USP11) (Internal Region) antibodyUSP11 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 11 (USP11) (AA 201-300) antibodyUSP11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 11 (USP11) (C-Term) antibodyVerified USP11 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 11 (USP11) (Internal Region) antibodyUSP11 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 11 (USP11) (AA 279-308), (N-Term) antibodyUSP11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4293-4294 unconjugated
anti-Ubiquitin Specific Peptidase 11 (USP11) (N-Term) antibodyUSP11 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- USP11 (Ubiquitin Specific Peptidase 11 (USP11))
-
别名
- USP11
-
背景
-
Description: Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains (PubMed:12084015, PubMed:15314155, PubMed:17897950, PubMed:19874889, PubMed:20233726, PubMed:24724799). Inhibits the degradation of target proteins by the proteasome (PubMed:12084015). Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains (in vitro) (PubMed:24724799). Plays a role in the regulation of pathways leading to NF-kappa-B activation (PubMed:17897950, PubMed:19874889). Plays a role in the regulation of DNA repair after double-stranded DNA breaks (PubMed:15314155, PubMed:20233726). Acts as a chromatin regulator via its association with the Polycomb group (PcG) multiprotein PRC1-like complex, may act by deubiquitinating components of the PRC1-like complex (PubMed:20601937).
Gene: USP11
-
分子量
- 109 kDa
-
基因ID
- 8237
-
UniProt
- P51784
抗原
-
