IFIT5 抗体 (Internal Region)
Quick Overview for IFIT5 抗体 (Internal Region) (ABIN6258319)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- IFIT5 Antibody detects endogenous levels of total IFIT5.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human IFIT5, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5) (AA 107-320) antibody
IFIT5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5) antibodyIFIT5 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5) (AA 1-482) antibodyIFIT5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5) (AA 182-231) antibodyIFIT5 适用: 人, 马, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5) (AA 110-159) antibodyIFIT5 适用: 人, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5) (N-Term) antibodyIFIT5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- IFIT5 (Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5))
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别名
- IFIT5
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背景
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Description: Interferon-induced RNA-binding protein involved in the human innate immune response. Has a broad and adaptable RNA structure recognition important for RNA recognition specificity in antiviral defense. Binds precursor and processed tRNAs as well as poly-U-tailed tRNA fragments (PubMed:25092312, PubMed:23317505, PubMed:23774268). Specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner (PubMed:23334420). Also recognizes and selectively binds AT-rich dsDNA (PubMed:23774268). Additionally, as a mediator in innate immunity, regulates positively IKK-NFKB signaling by sinergizing the recruitment of IKK to MAP3K7 (PubMed:26334375).
Gene: IFIT5
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分子量
- 50 kDa
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基因ID
- 24138
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UniProt
- Q13325
抗原
-
