RHOH 抗体 (Internal Region)
Quick Overview for RHOH 抗体 (Internal Region) (ABIN6258315)
抗原
See all RHOH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- RhoH Antibody detects endogenous levels of total RhoH.
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预测反应
- Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human RhoH, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Ras Homolog Family Member H (RHOH) (C-Term) antibody
RHOH 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) (AA 1-188) antibodyRHOH 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) antibodyRHOH 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) (AA 141-190) antibodyRHOH 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) (AA 1-191) antibodyRHOH 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) antibodyRHOH 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) (AA 1-191) antibodyRHOH 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Ras Homolog Family Member H (RHOH) (AA 1-191) antibodyRHOH 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) (C-Term) antibodyRHOH 适用: 人, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) (AA 141-190) antibodyRHOH 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- RHOH (Ras Homolog Family Member H (RHOH))
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别名
- RHOH
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背景
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Description: Negative regulator of hematopoietic progenitor cell proliferation, survival and migration. Critical regulator of thymocyte development and T-cell antigen receptor (TCR) signaling by mediating recruitment and activation of ZAP70. Required for phosphorylation of CD3Z, membrane translocation of ZAP70 and subsequent activation of the ZAP70-mediated pathways. Essential for efficient beta-selection and positive selection by promoting the ZAP70-dependent phosphorylation of the LAT signalosome during pre-TCR and TCR signaling. Crucial for thymocyte maturation during DN3 to DN4 transition and during positive selection. Plays critical roles in mast cell function by facilitating phosphorylation of SYK in Fc epsilon RI-mediated signal transduction. Essential for the phosphorylation of LAT, LCP2, PLCG1 and PLCG2 and for Ca2+ mobilization in mast cells (By similarity). Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. Inhibits the activation of NF-kappa-B by TNF and IKKB and the activation of CRK/p38 by TNF. Inhibits activities of RAC1, RHOA and CDC42. Negatively regulates leukotriene production in neutrophils.
Gene: RHOH
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分子量
- 21 kDa
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基因ID
- 399
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UniProt
- Q15669
抗原
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