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MARK3 抗体 (N-Term)

This anti-MARK3 antibody is a 兔 多克隆 antibody detecting MARK3 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6258273
发货至: 中国

Quick Overview for MARK3 抗体 (N-Term) (ABIN6258273)

抗原

See all MARK3 抗体
MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

适用

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人, 小鼠, 大鼠

宿主

  • 50
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  • 1

克隆类型

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多克隆

标记

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This MARK3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    N-Term

    特异性

    MARK3 Antibody detects endogenous levels of total MARK3.

    预测反应

    Pig,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human MARK3, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

    别名

    MARK3

    背景

    Description: Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed:16980613). Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714).

    Gene: MARK3

    分子量

    85 kDa

    基因ID

    4140

    UniProt

    P27448

    途径

    SARS-CoV-2 Protein Interactome
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