Ube2t 抗体 (Internal Region)
Quick Overview for Ube2t 抗体 (Internal Region) (ABIN6258234)
抗原
See all Ube2t 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- UBE2T Antibody detects endogenous levels of total UBE2T.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human UBE2T, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Ubiquitin-Conjugating Enzyme E2T (Ube2t) (AA 1-197) antibody
Ube2t 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1E12-4A3 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2T (Ube2t) (AA 1-197) antibodyUbe2t 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2A12-4F11 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2T (Ube2t) (AA 1-197) antibodyUbe2t 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2T (Ube2t) (C-Term) antibodyUbe2t 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2T (Ube2t) (C-Term) antibodyVerified Ube2t 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2T (Ube2t) (Internal Region) antibodyUbe2t 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2T (Ube2t) (N-Term) antibodyUbe2t 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2T (Ube2t) (Internal Region) antibodyUbe2t 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
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别名
- UBE2T
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背景
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Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair. Acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway (PubMed:16916645, PubMed:17938197, PubMed:19111657, PubMed:19589784, PubMed:28437106). Also mediates monoubiquitination of FANCL and FANCI (PubMed:16916645, PubMed:17938197, PubMed:19111657, PubMed:19589784). May contribute to ubiquitination and degradation of BRCA1 (PubMed:19887602). In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination (PubMed:20061386).
Gene: UBE2T
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分子量
- 22 kDa
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基因ID
- 29089
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UniProt
- Q9NPD8
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途径
- Chromatin Binding
抗原
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