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GPR56 抗体

This anti-GPR56 antibody is a 兔 多克隆 antibody detecting GPR56 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN6258204
发货至: 中国

Quick Overview for GPR56 抗体 (ABIN6258204)

抗原

See all GPR56 抗体
GPR56 (G Protein-Coupled Receptor 56 (GPR56))

适用

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宿主

  • 34
  • 6

克隆类型

  • 36
  • 4
多克隆

标记

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This GPR56 antibody is un-conjugated

应用范围

  • 32
  • 17
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 特异性

    GPR56 antibody detects endogenous levels of total GPR56

    交叉反应

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000 IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    GPR56 (G Protein-Coupled Receptor 56 (GPR56))

    别名

    GPR56

    背景

    Description: Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination (By similarity). Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12 (PubMed:22238662). Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (By similarity). Plays a critical role in cancer progression by inhibiting VEGFA production threreby inhibiting angiogenesis through a signaling pathway mediated by PRKCA (PubMed:16757564, PubMed:21724588). Plays an essential role in testis development (By similarity).

    Gene: ADGRG1

    分子量

    78 kDa

    基因ID

    9289

    UniProt

    Q9Y653
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