DYRK3 抗体
Quick Overview for DYRK3 抗体 (ABIN6258128)
抗原
See all DYRK3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- RED Antibody detects endogenous levels of total RED
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide
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亚型
- IgG
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应用备注
- WB 1:500~1:1000, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))
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别名
- RED
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背景
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Description: Involved in pre-mRNA splicing as a component of the spliceosome (PubMed:28781166). Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Required for normal mitotic cell cycle progression (PubMed:22351768, PubMed:24252166). Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint (PubMed:22351768). Required for normal accumulation of SMU1 (PubMed:24945353).
Gene: IK
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分子量
- 66 kDa
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基因ID
- 3550
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UniProt
- Q13123
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途径
- Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
抗原
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