CKLF 抗体
Quick Overview for CKLF 抗体 (ABIN6258091)
抗原
See all CKLF 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- CKLF6 Antibody detects endogenous levels of total CKLF6
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交叉反应
- 人, 小鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide
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亚型
- IgG
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anti-Chemokine-Like Factor (CKLF) (AA 1-100) antibody
CKLF 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine-Like Factor (CKLF) (C-Term) antibodyCKLF 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine-Like Factor (CKLF) antibodyCKLF 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine-Like Factor (CKLF) (C-Term) antibodyCKLF 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine-Like Factor (CKLF) (AA 1-67) antibodyCKLF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine-Like Factor (CKLF) (N-Term) antibodyCKLF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500~1:1000, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- CKLF (Chemokine-Like Factor (CKLF))
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别名
- CKLF6
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背景
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Description: Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its STUB1-mediated ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately triggering T-cell anergy.
Gene: CMTM6
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分子量
- 25 kDa
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基因ID
- 54918
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UniProt
- Q9NX76
抗原
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