COPS2 抗体 (Internal Region)
Quick Overview for COPS2 抗体 (Internal Region) (ABIN6258029)
抗原
See all COPS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- COPS2 Antibody detects endogenous levels of total COPS2.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human COPS2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (AA 344-443) antibody
COPS2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4B12 unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (C-Term) antibodyCOPS2 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (C-Term) antibodyVerified COPS2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (AA 1-310) antibodyCOPS2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (N-Term) antibodyCOPS2 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (AA 1-310) antibodyCOPS2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) antibodyCOPS2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (N-Term) antibodyCOPS2 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 豚鼠, 兔, 猴, Pig, 小鸡, 非洲爪蟾, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (AA 1-50) antibodyCOPS2 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 小鸡, 非洲爪蟾 WB, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (N-Term) antibodyCOPS2 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 豚鼠, 兔, 猴, Drosophila melanogaster, Pig, 小鸡, 非洲爪蟾, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))
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别名
- COPS2
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背景
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Description: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.
Gene: COPS2
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分子量
- 55 kDa
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基因ID
- 9318
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UniProt
- P61201
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途径
- Cell Division Cycle
抗原
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