PRKG2 抗体 (N-Term)
Quick Overview for PRKG2 抗体 (N-Term) (ABIN6258017)
抗原
See all PRKG2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- CGK2 Antibody detects endogenous levels of total CGK2.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CGK2, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (AA 714-744), (C-Term) antibody
PRKG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01036 unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (Internal Region) antibodyPRKG2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (Ser363), (Thr359) antibodyPRKG2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) antibodyPRKG2 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (Ser126) antibodyPRKG2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (AA 453-728) antibodyPRKG2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (AA 1-100) antibodyPRKG2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (N-Term) antibodyPRKG2 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (C-Term) antibodyPRKG2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- PRKG2 (Protein Kinase, CGMP-Dependent, Type II (PRKG2))
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别名
- PRKG2
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背景
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Description: Crucial regulator of intestinal secretion and bone growth (By similarity). Phosphorylates and activates CFTR on the plasma membrane. Plays a key role in intestinal secretion by regulating cGMP-dependent translocation of CFTR in jejunum (By similarity). Acts downstream of NMDAR to activate the plasma membrane accumulation of GRIA1/GLUR1 in synapse and increase synaptic plasticity. Phosphorylates GRIA1/GLUR1 at Ser-863 (By similarity). Acts as regulator of gene expression and activator of the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2 in mechanically stimulated osteoblasts. Under fluid shear stress, mediates ERK activation and subsequent induction of FOS, FOSL1/FRA1, FOSL2/FRA2 and FOSB that play a key role in the osteoblast anabolic response to mechanical stimulation (By similarity).
Gene: PRKG2
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分子量
- 87 kDa
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基因ID
- 5593
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UniProt
- Q13237
抗原
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