CREB3L2 抗体 (Internal Region)
Our Local Distributor
北京 101111
Quick Overview for CREB3L2 抗体 (Internal Region) (ABIN6257984)
抗原
See all CREB3L2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
特异性
- CREB3L2 Antibody detects endogenous levels of total CREB3L2.
-
预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human CREB3L2, corresponding to a region within the internal amino acids.
-
亚型
- IgG
-
-
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (N-Term) antibody
CREB3L2 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (AA 1-247) antibodyCREB3L2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (N-Term) antibodyVerified CREB3L2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (Internal Region) antibodyCREB3L2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (AA 421-518) antibodyCREB3L2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (AA 34-72) antibodyCREB3L2 适用: 人, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (Internal Region) antibodyVerified CREB3L2 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (AA 490-517), (C-Term) antibodyCREB3L2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB24309 unconjugated
-
-
应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- CREB3L2 (CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2))
-
别名
- CREB3L2
-
背景
-
Description: Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A, which promotes the transport and secretion of cartilage matrix proteins, and possibly that of ER biogenesis-related genes (By similarity). In a neuroblastoma cell line, protects cells from ER stress-induced death (PubMed:17178827). In vitro activates transcription of target genes via direct binding to the CRE site (PubMed:17178827).
Gene: CREB3L2
-
分子量
- 58 kDa
-
基因ID
- 64764
-
UniProt
- Q70SY1
-
途径
- Thyroid Hormone Synthesis
抗原
-
