CREB3L2 抗体 (Internal Region)
Quick Overview for CREB3L2 抗体 (Internal Region) (ABIN6257984)
抗原
See all CREB3L2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- CREB3L2 Antibody detects endogenous levels of total CREB3L2.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CREB3L2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (N-Term) antibody
CREB3L2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (AA 1-247) antibodyCREB3L2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (N-Term) antibodyVerified CREB3L2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (Internal Region) antibodyCREB3L2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (AA 421-518) antibodyCREB3L2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (AA 34-72) antibodyCREB3L2 适用: 人, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (Internal Region) antibodyVerified CREB3L2 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (AA 490-517), (C-Term) antibodyCREB3L2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB24309 unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) (Internal Region) antibodyCREB3L2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- CREB3L2 (CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2))
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别名
- CREB3L2
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背景
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Description: Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A, which promotes the transport and secretion of cartilage matrix proteins, and possibly that of ER biogenesis-related genes (By similarity). In a neuroblastoma cell line, protects cells from ER stress-induced death (PubMed:17178827). In vitro activates transcription of target genes via direct binding to the CRE site (PubMed:17178827).
Gene: CREB3L2
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分子量
- 58 kDa
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基因ID
- 64764
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UniProt
- Q70SY1
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途径
- Thyroid Hormone Synthesis
抗原
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