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BCOR 抗体 (Internal Region)

This anti-BCOR antibody is a 兔 多克隆 antibody detecting BCOR in WB, ELISA, IHC, ICC 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN6257962
发货至: 中国

Quick Overview for BCOR 抗体 (Internal Region) (ABIN6257962)

抗原

See all BCOR 抗体
BCOR (BCL6 Co-Repressor (BCOR))

适用

  • 33
  • 16
  • 1
人, 小鼠

宿主

  • 31
  • 4
  • 1

克隆类型

  • 35
  • 1
多克隆

标记

  • 25
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BCOR antibody is un-conjugated

应用范围

  • 21
  • 14
  • 12
  • 9
  • 6
  • 3
  • 3
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    特异性

    BCOR Antibody detects endogenous levels of total BCOR.

    预测反应

    Pig,Bovine,Sheep,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human BCOR, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    BCOR (BCL6 Co-Repressor (BCOR))

    别名

    BCOR

    背景

    Description: Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A, impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells, the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).

    Gene: BCOR

    分子量

    192 kDa

    基因ID

    54880

    UniProt

    Q6W2J9
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