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ARHGAP18 抗体 (Internal Region)

This anti-ARHGAP18 antibody is a 兔 多克隆 antibody detecting ARHGAP18 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人 和 大鼠.
产品编号 ABIN6257900
发货至: 中国

Quick Overview for ARHGAP18 抗体 (Internal Region) (ABIN6257900)

抗原

See all ARHGAP18 抗体
ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

适用

  • 26
  • 5
  • 5
  • 1
人, 大鼠

宿主

  • 26

克隆类型

  • 26
多克隆

标记

  • 17
  • 3
  • 2
  • 2
  • 1
  • 1
This ARHGAP18 antibody is un-conjugated

应用范围

  • 22
  • 18
  • 11
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 7
    • 7
    • 7
    • 1
    • 1
    • 1
    Internal Region

    特异性

    RHG18 Antibody detects endogenous levels of total RHG18.

    预测反应

    Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human RHG18, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

    别名

    ARHGAP18

    背景

    Description: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). Regulates cell shape, spreading, and migration (PubMed:21865595).

    Gene: ARHGAP18

    分子量

    75 kDa

    基因ID

    93663

    UniProt

    Q8N392
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