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TRIP13 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects TRIP13 in WB, ELISA, ICC 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN6257873
发货至: 中国
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Quick Overview for TRIP13 抗体 (C-Term) (ABIN6257873)

抗原

See all TRIP13 抗体
TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

适用

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人, 小鼠, 大鼠

宿主

  • 47
  • 3

克隆类型

  • 47
  • 3
多克隆

标记

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This TRIP13 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

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    • 1
    • 1
    • 1
    • 1
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    C-Term

    特异性

    TRIP13 Antibody detects endogenous levels of total TRIP13.

    预测反应

    Bovine,Horse,Sheep,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human TRIP13, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

    别名

    TRIP13

    背景

    Description: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity). Plays a role in mitotic spindle assembly checkpoint (SAC) activation (PubMed:28553959).

    Gene: TRIP13

    分子量

    48 kDa

    基因ID

    9319

    UniProt

    Q15645
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