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DOCK1 抗体 (C-Term)

This anti-DOCK1 antibody is a 兔 多克隆 antibody detecting DOCK1 in ELISA, WB, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6257863
发货至: 中国

Quick Overview for DOCK1 抗体 (C-Term) (ABIN6257863)

抗原

See all DOCK1 抗体
DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 47
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多克隆

标记

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This DOCK1 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
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    C-Term

    特异性

    DOCK1 Antibody detects endogenous levels of total DOCK1.

    预测反应

    Zebrafish,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human DOCK1, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

    别名

    DOCK1

    背景

    Description: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152).

    Gene: DOCK1

    分子量

    215 kDa

    基因ID

    1793

    UniProt

    Q14185

    途径

    Signaling of Hepatocyte Growth Factor Receptor
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