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MED8 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects MED8 in WB, ELISA, IF 和 ICC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN6257837
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for MED8 抗体 (C-Term) (ABIN6257837)

抗原

See all MED8 抗体
MED8 (Mediator Complex Subunit 8 (MED8))

适用

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人, 小鼠, 大鼠

宿主

  • 25
  • 5

克隆类型

  • 26
  • 4
多克隆

标记

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This MED8 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 7
    • 3
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    • 1
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    C-Term

    特异性

    MED8 Antibody detects endogenous levels of total MED8.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human MED8, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    MED8 (Mediator Complex Subunit 8 (MED8))

    别名

    MED8

    背景

    Description: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.

    Gene: MED8

    分子量

    29 kDa

    基因ID

    112950

    UniProt

    Q96G25

    途径

    Regulation of Lipid Metabolism by PPARalpha
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