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ERI1 抗体 (C-Term)

The 兔 多克隆 anti-ERI1 antibody is suitable to detect ERI1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, ICC 和 IF.
产品编号 ABIN6257805
发货至: 中国
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中国
北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ERI1 抗体 (C-Term) (ABIN6257805)

抗原

See all ERI1 抗体
ERI1 (Exoribonuclease 1 (ERI1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ERI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    特异性

    ERI1 Antibody detects endogenous levels of total ERI1.

    预测反应

    Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human ERI1, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    ERI1 (Exoribonuclease 1 (ERI1))

    别名

    ERI1

    背景

    Description: RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.

    Gene: ERI1

    分子量

    40 kDa

    基因ID

    90459

    UniProt

    Q8IV48
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