电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

OPRK1 抗体 (N-Term)

This anti-OPRK1 antibody is a 兔 多克隆 antibody detecting OPRK1 in WB, ELISA, IF 和 ICC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6257760
发货至: 中国

Quick Overview for OPRK1 抗体 (N-Term) (ABIN6257760)

抗原

See all OPRK1 抗体
OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

适用

  • 49
  • 46
  • 40
  • 3
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 63
  • 2
  • 1

克隆类型

  • 65
  • 1
多克隆

标记

  • 32
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This OPRK1 antibody is un-conjugated

应用范围

  • 41
  • 25
  • 11
  • 10
  • 9
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 12
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    OPRK1 Antibody detects endogenous levels of total OPRK1.

    预测反应

    Bovine,Horse

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human OPRK1, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

    别名

    OPRK1

    背景

    Description: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.

    Gene: OPRK1

    分子量

    48 kDa

    基因ID

    4986

    UniProt

    P41145
You are here:
Chat with us!