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HOPX 抗体 (C-Term)

The 兔 多克隆 anti-HOPX antibody (ABIN6257752) specifically detects HOPX in WB, ELISA 和 IHC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN6257752
发货至: 中国
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Quick Overview for HOPX 抗体 (C-Term) (ABIN6257752)

抗原

See all HOPX 抗体
HOPX (HOP Homeobox (HOPX))

适用

  • 46
  • 22
  • 18
人, 小鼠

宿主

  • 45
  • 3

克隆类型

  • 45
  • 3
多克隆

标记

  • 22
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HOPX antibody is un-conjugated

应用范围

  • 43
  • 21
  • 14
  • 13
  • 5
  • 5
  • 5
  • 3
  • 3
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 12
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term

    特异性

    HOP Antibody detects endogenous levels of total HOP.

    预测反应

    Pig,Bovine,Horse,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human HOP, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    有效期

    12 months
  • 抗原

    HOPX (HOP Homeobox (HOPX))

    别名

    HOPX

    背景

    Description: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding (PubMed:27708256).

    Gene: HOPX

    分子量

    8 kDa

    基因ID

    84525

    UniProt

    Q9BPY8

    途径

    Regulation of Muscle Cell Differentiation
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