GNA13 抗体 (N-Term)
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- 抗原 See all GNA13 抗体
- GNA13 (Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GNA13 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- GNA13 Antibody detects endogenous levels of total GNA13.
- 预测反应
- Pig,Rabbit,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human GNA13, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product GNA13 Primary Antibody
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anti-Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) (AA 1-377) antibody
GNA13 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6F6-B5 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) antibodyGNA13 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) (N-Term) antibodyGNA13 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, Pig, Hamster, 猴, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) antibodyGNA13 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) (AA 184-212) antibodyGNA13 适用: 人 WB 宿主: 兔 Polyclonal RB36839 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) (N-Term) antibodyGNA13 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- GNA13 (Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13))
- 别名
- GNA13 (GNA13 产品)
- 别名
- Galpha13 antibody, gna13 antibody, wu:fe25e05 antibody, zgc:112436 antibody, Gna13 antibody, fj64c01 antibody, wu:fj64c01 antibody, GNA13 antibody, G13 antibody, AU024132 antibody, AU043124 antibody, G protein subunit alpha 13 antibody, guanine nucleotide binding protein (G protein), alpha 13a antibody, guanine nucleotide binding protein (G protein), alpha 13b antibody, guanine nucleotide binding protein, alpha 13 antibody, Gna13 antibody, gna13a antibody, gna13b antibody, GNA13 antibody
- 背景
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Description: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:15240885, PubMed:16787920, PubMed:16705036, PubMed:27084452). Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:15240885, PubMed:12515866). GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1) (By similarity). Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway (PubMed:16787920, PubMed:16705036, PubMed:27084452). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (PubMed:11976333).
Gene: GNA13
- 分子量
- 44 kDa
- 基因ID
- 10672
- UniProt
- Q14344
- 途径
- CXCR4-mediated Signaling Events
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