GNA13 抗体 (N-Term)
Quick Overview for GNA13 抗体 (N-Term) (ABIN6257750)
抗原
See all GNA13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- GNA13 Antibody detects endogenous levels of total GNA13.
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预测反应
- Pig,Rabbit,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human GNA13, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) (AA 1-377) antibody
GNA13 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6F6-B5 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) antibodyGNA13 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) (N-Term) antibodyGNA13 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, Hamster, 猴, Pig, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) antibodyGNA13 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) (AA 184-212) antibodyGNA13 适用: 人 WB 宿主: 兔 Polyclonal RB36839 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) (N-Term) antibodyGNA13 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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有效期
- 12 months
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- GNA13 (Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13))
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别名
- GNA13
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背景
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Description: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:15240885, PubMed:16787920, PubMed:16705036, PubMed:27084452). Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:15240885, PubMed:12515866). GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1) (By similarity). Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway (PubMed:16787920, PubMed:16705036, PubMed:27084452). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (PubMed:11976333).
Gene: GNA13
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分子量
- 44 kDa
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基因ID
- 10672
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UniProt
- Q14344
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途径
- CXCR4-mediated Signaling Events
抗原
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