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DKK3 抗体 (C-Term)

The 兔 多克隆 anti-DKK3 antibody (ABIN6257704) specifically detects DKK3 in WB, ELISA, ICC 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN6257704
发货至: 中国
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Quick Overview for DKK3 抗体 (C-Term) (ABIN6257704)

抗原

See all DKK3 抗体
DKK3

适用

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人, 小鼠

宿主

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克隆类型

  • 63
  • 20
多克隆

标记

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This DKK3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    特异性

    DKK3 Antibody detects endogenous levels of total DKK3.

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human DKK3, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    DKK3

    背景

    Description: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

    Gene: DKK3

    分子量

    45 kDa

    基因ID

    27122

    UniProt

    Q9UBP4
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