CHP 抗体 (Internal Region)
Quick Overview for CHP 抗体 (Internal Region) (ABIN6257590)
抗原
See all CHP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- CHP Antibody detects endogenous levels of total CHP.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CHP, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Calcium Binding Protein P22 (CHP) (AA 2-195) antibody
CHP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein P22 (CHP) (AA 1-195) antibodyCHP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein P22 (CHP) (Internal Region) antibodyCHP 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein P22 (CHP) antibodyCHP 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein P22 (CHP) (AA 35-84) antibodyCHP 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein P22 (CHP) antibodyCHP 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein P22 (CHP) (N-Term) antibodyCHP 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein P22 (CHP) (Internal Region) antibodyCHP 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein P22 (CHP) (AA 1-66) antibodyCHP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Calcium Binding Protein P22 (CHP) (AA 2-195) antibodyCHP 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- CHP (Calcium Binding Protein P22 (CHP))
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别名
- CHP1
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背景
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Description: Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na+/H+ exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Affects the pH sensitivity of SLC9A1/NHE1 by increasing its sensitivity at acidic pH . Required for the stabilization and localization of SLC9A1/NHE1 at the plasma membrane. Inhibits serum- and GTPase-stimulated Na+/H+ exchange. Plays a role as an inhibitor of ribosomal RNA transcription by repressing the nucleolar UBF1 transcriptional activity. May sequester UBF1 in the nucleoplasm and limit its translocation to the nucleolus. Associates to the ribosomal gene promoter. Acts as a negative regulator of the calcineurin/NFAT signaling pathway. Inhibits NFAT nuclear translocation and transcriptional activity by suppressing the calcium-dependent calcineurin phosphatase activity. Also negatively regulates the kinase activity of the apoptosis-induced kinase STK17B. Inhibits both STK17B auto- and substrate-phosphorylations in a calcium-dependent manner.
Gene: CHP1
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分子量
- 22 kDa
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基因ID
- 11261
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UniProt
- Q99653
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途径
- Proton Transport, Regulation of Carbohydrate Metabolic Process, VEGF Signaling
抗原
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