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TEAD3 抗体 (Internal Region)

The 兔 多克隆 anti-TEAD3 antibody is suitable to detect TEAD3 in samples from 人 和 小鼠. It has been validated for ELISA, WB, IF 和 ICC.
产品编号 ABIN6257529
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TEAD3 抗体 (Internal Region) (ABIN6257529)

抗原

See all TEAD3 抗体
TEAD3 (TEA Domain Family Member 3 (TEAD3))

适用

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人, 小鼠

宿主

  • 44
  • 3

克隆类型

  • 45
  • 2
多克隆

标记

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This TEAD3 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 9
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    • 2
    • 2
    • 2
    • 1
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    Internal Region

    特异性

    TEAD3 Antibody detects endogenous levels of total TEAD3.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human TEAD3, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    TEAD3 (TEA Domain Family Member 3 (TEAD3))

    别名

    TEAD3

    背景

    Description: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.

    Gene: TEAD3

    分子量

    49 kDa

    基因ID

    7005

    UniProt

    Q99594

    途径

    Regulation of Lipid Metabolism by PPARalpha
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