RNF125 抗体 (Internal Region)
Quick Overview for RNF125 抗体 (Internal Region) (ABIN6257463)
抗原
See all RNF125 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- RNF125 Antibody detects endogenous levels of total RNF125.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human RNF125, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Ring Finger Protein 125 (RNF125) (AA 143-231) antibody
RNF125 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D3 unconjugated
anti-Ring Finger Protein 125 (RNF125) (AA 1-232) antibodyRNF125 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (C-Term) antibodyVerified RNF125 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (AA 143-231) antibodyRNF125 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (AA 143-231) antibodyRNF125 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (C-Term) antibodyRNF125 适用: 人, 小鼠, 大鼠, 猴, Cow, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (AA 1-105) antibodyRNF125 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (Center) antibodyRNF125 适用: 人, 小鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- RNF125 (Ring Finger Protein 125 (RNF125))
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别名
- RNF125
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背景
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Description: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins, such as DDX58/RIG-I, MAVS/IPS1, IFIH1/MDA5, JAK1 and p53/TP53 (PubMed:15843525, PubMed:17460044, PubMed:17643463, PubMed:26027934, PubMed:26471729, PubMed:25591766, PubMed:27411375). Acts as a negative regulator of type I interferon production by mediating ubiquitination of DDX58/RIG-I at 'Lys-181', leading to DDX58/RIG-I degradation (PubMed:17460044, PubMed:26471729). Mediates ubiquitination and subsequent degradation of p53/TP53 (PubMed:25591766). Mediates ubiquitination and subsequent degradation of JAK1 (PubMed:26027934). Acts as a positive regulator of T-cell activation (PubMed:15843525).
Gene: RNF125
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分子量
- 26 kDa
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基因ID
- 54941
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UniProt
- Q96EQ8
抗原
-
