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PAK1IP1 抗体 (C-Term)

This anti-PAK1IP1 antibody is a 兔 多克隆 antibody detecting PAK1IP1 in WB, ELISA, IF, IHC 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6257409
发货至: 中国

Quick Overview for PAK1IP1 抗体 (C-Term) (ABIN6257409)

抗原

See all PAK1IP1 抗体
PAK1IP1 (PAK1 Interacting Protein 1 (PAK1IP1))

适用

  • 10
  • 4
  • 3
人, 小鼠

宿主

  • 6
  • 5

克隆类型

  • 8
  • 3
多克隆

标记

  • 11
This PAK1IP1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
  • 抗原表位

    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    PAK1IP1 Antibody detects endogenous levels of total PAK1IP1.

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human PAK1IP1, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    有效期

    12 months
  • 抗原

    PAK1IP1 (PAK1 Interacting Protein 1 (PAK1IP1))

    别名

    PAK1IP1

    背景

    Description: Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly (PubMed:24120868).

    Gene: PAK1IP1

    分子量

    ?48 kDa

    基因ID

    55003

    UniProt

    Q9NWT1

    途径

    Telomere Maintenance
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