MAPKSP1 抗体 (Internal Region)
Quick Overview for MAPKSP1 抗体 (Internal Region) (ABIN6257364)
抗原
See all MAPKSP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- LAMTOR3 Antibody detects endogenous levels of total LAMTOR3.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human LAMTOR3, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1) antibody
MAPKSP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1) (AA 1-124) antibodyMAPKSP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1) (AA 1-124) antibodyMAPKSP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1) (AA 1-87) antibodyMAPKSP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1) (AA 13-62) antibodyMAPKSP1 适用: 人, Cow, 马, 兔, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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有效期
- 12 months
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- MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
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别名
- LAMTOR3
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背景
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Description: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
Gene: LAMTOR3
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基因ID
- 8649
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UniProt
- Q9UHA4
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途径
- PI3K-Akt Signaling
抗原
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