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MDFI 抗体 (Internal Region)

This anti-MDFI antibody is a 兔 多克隆 antibody detecting MDFI in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6257357
发货至: 中国

Quick Overview for MDFI 抗体 (Internal Region) (ABIN6257357)

抗原

See all MDFI 抗体
MDFI (MyoD Family Inhibitor (MDFI))

适用

  • 33
  • 9
  • 5
  • 1
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  • 1
人, 大鼠, 小鼠

宿主

  • 30
  • 2
  • 2

克隆类型

  • 33
  • 1
多克隆

标记

  • 13
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This MDFI antibody is un-conjugated

应用范围

  • 13
  • 13
  • 11
  • 10
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    特异性

    MDFI Antibody detects endogenous levels of total MDFI.

    预测反应

    Pig,Bovine,Horse,Sheep,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human MDFI, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    MDFI (MyoD Family Inhibitor (MDFI))

    别名

    MDFI

    背景

    Description: Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By similarity).

    Gene: MDFI

    分子量

    25 kDa

    基因ID

    4188

    UniProt

    Q99750

    途径

    Maintenance of Protein Location
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