XRN1 抗体 (N-Term)
Quick Overview for XRN1 抗体 (N-Term) (ABIN6257273)
抗原
See all XRN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- XRN1 Antibody detects endogenous levels of total XRN1.
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预测反应
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human XRN1, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1394-1706) antibody
XRN1 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1567-1723) antibodyXRN1 适用: 大鼠 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1389-1423), (C-Term) antibodyXRN1 适用: 人 WB 宿主: 兔 Polyclonal RB49366 unconjugated
anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1-459) antibodyXRN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1260-1309) antibodyXRN1 适用: 人, 小鼠, 大鼠, 豚鼠, Pig, 兔, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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有效期
- 12 months
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- XRN1 (5'-3' Exoribonuclease 1 (XRN1))
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别名
- XRN1
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背景
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Description: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
Gene: XRN1
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分子量
- 194 kDa
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基因ID
- 54464
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UniProt
- Q8IZH2
抗原
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