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GDF15 抗体 (N-Term)

The 兔 多克隆 anti-GDF15 antibody (ABIN6257251) specifically detects GDF15 in WB, ELISA, IHC, ICC 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN6257251
发货至: 中国
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Quick Overview for GDF15 抗体 (N-Term) (ABIN6257251)

抗原

See all GDF15 抗体
GDF15 (Growth Differentiation Factor 15 (GDF15))

适用

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宿主

  • 100
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克隆类型

  • 98
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多克隆

标记

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This GDF15 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

    • 15
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    N-Term

    特异性

    GDF15 Antibody detects endogenous levels of total GDF15.

    预测反应

    Pig,Bovine,Sheep,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human GDF15, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    GDF15 (Growth Differentiation Factor 15 (GDF15))

    别名

    GDF15

    背景

    Description: Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435). Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886). On hepatocytes, inhibits growth hormone signaling (By similarity).

    Gene: GDF15

    分子量

    37 kDa

    基因ID

    9518

    UniProt

    Q99988

    途径

    SARS-CoV-2 Protein Interactome
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