Cyclin Y 抗体 (Internal Region)
Quick Overview for Cyclin Y 抗体 (Internal Region) (ABIN6257123)
抗原
See all Cyclin Y (CCNY) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- CCNY Antibody detects endogenous levels of total CCNY.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CCNY, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Cyclin Y (CCNY) (AA 2-170) antibody
CCNY 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin Y (CCNY) (AA 140-169) antibodyCCNY 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB21871 unconjugated
anti-Cyclin Y (CCNY) (AA 146-195) antibodyCCNY 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin Y (CCNY) (AA 60-120) antibodyCCNY 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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有效期
- 12 months
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- Cyclin Y (CCNY)
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别名
- CCNY
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背景
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Description: Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Gene: CCNY
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分子量
- 39 kDa
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基因ID
- 219771
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UniProt
- Q8ND76
抗原
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