CSNK2A2 抗体 (N-Term)
Quick Overview for CSNK2A2 抗体 (N-Term) (ABIN6257088)
抗原
See all CSNK2A2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- CSNK2A2 Antibody detects endogenous levels of total CSNK2A2.
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预测反应
- Pig,Bovine,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CSNK2A2, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2) (AA 194-350) antibody
CSNK2A2 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2) (AA 1-100) antibodyCSNK2A2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2) (AA 1-350) antibodyCSNK2A2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2) (AA 8-350) antibodyCSNK2A2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2) (AA 251-300) antibodyCSNK2A2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 豚鼠, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2) (C-Term) antibodyCSNK2A2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2) antibodyCSNK2A2 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2) (AA 300-350), (C-Term) antibodyCSNK2A2 适用: 人, Cow, 犬, 兔, Pig WB, IHC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2) (AA 1-350) antibodyCSNK2A2 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 4F2 unconjugated
anti-Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2) antibody (HRP)CSNK2A2 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
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应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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有效期
- 12 months
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- CSNK2A2 (Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2))
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别名
- CSNK2A2
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背景
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Description: Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation. Can also negatively regulate apoptosis. Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3. Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activation of CASP8. Regulates transcription by direct phosphorylation of RNA polymerases I, II, III and IV. Also phosphorylates and regulates numerous transcription factors including NF-kappa-B, STAT1, CREB1, IRF1, IRF2, ATF1, SRF, MAX, JUN, FOS, MYC and MYB. Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, which is essential for chaperone function. Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1. Acts as an ectokinase that phosphorylates several extracellular proteins. During viral infection, phosphorylates various proteins involved in the viral life cycles of EBV, HSV, HBV, HCV, HIV, CMV and HPV.
Gene: CSNK2A2
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分子量
- 41 kDa
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基因ID
- 1459
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UniProt
- P19784
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途径
- SARS-CoV-2 Protein Interactome
抗原
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