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ARHGAP17 抗体 (Internal Region)

This anti-ARHGAP17 antibody is a 兔 多克隆 antibody detecting ARHGAP17 in WB, ELISA, IF 和 ICC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6257043
发货至: 中国

Quick Overview for ARHGAP17 抗体 (Internal Region) (ABIN6257043)

抗原

See all ARHGAP17 抗体
ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

适用

  • 29
  • 12
  • 11
  • 2
人, 大鼠, 小鼠

宿主

  • 31

克隆类型

  • 30
多克隆

标记

  • 19
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  • 1
  • 1
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  • 1
  • 1
  • 1
This ARHGAP17 antibody is un-conjugated

应用范围

  • 23
  • 14
  • 10
  • 4
  • 3
  • 2
  • 2
  • 1
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    Internal Region

    特异性

    RHG17 Antibody detects endogenous levels of total RHG17.

    预测反应

    Bovine,Horse,Rabbit,Dog,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human RHG17, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

    别名

    ARHGAP17

    背景

    Description: Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca2+-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.

    Gene: ARHGAP17

    分子量

    100 kDa

    基因ID

    55114

    UniProt

    Q68EM7
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