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CNOT7 抗体 (C-Term)

This 兔 多克隆 anti-CNOT7 antibody specifically detects CNOT7 in WB, ELISA, IF 和 ICC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN6257033
发货至: 中国
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Quick Overview for CNOT7 抗体 (C-Term) (ABIN6257033)

抗原

See all CNOT7 抗体
CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

适用

  • 40
  • 20
  • 8
  • 4
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  • 3
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  • 3
  • 3
  • 3
  • 2
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  • 1
人, 小鼠

宿主

  • 33
  • 7

克隆类型

  • 34
  • 6
多克隆

标记

  • 25
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
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This CNOT7 antibody is un-conjugated

应用范围

  • 30
  • 22
  • 13
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  • 6
  • 3
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  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    CNOT7 Antibody detects endogenous levels of total CNOT7.

    预测反应

    Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human CNOT7, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

    别名

    CNOT7

    背景

    Description: Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.

    Gene: CNOT7

    分子量

    36 kDa

    基因ID

    29883

    UniProt

    Q9UIV1

    途径

    Ribonucleoprotein Complex Subunit Organization
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