PFKL 抗体 (C-Term)
Quick Overview for PFKL 抗体 (C-Term) (ABIN6257021)
抗原
See all PFKL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- K6PL Antibody detects endogenous levels of total K6PL.
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预测反应
- Pig,Bovine,Horse,Sheep,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human K6PL, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Phosphofructokinase, Liver (PFKL) (Center) antibody
PFKL 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphofructokinase, Liver (PFKL) (AA 229-479) antibodyPFKL 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphofructokinase, Liver (PFKL) (AA 700-780) antibodyPFKL 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphofructokinase, Liver (PFKL) (Middle Region) antibodyPFKL 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphofructokinase, Liver (PFKL) (C-Term) antibodyPFKL 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphofructokinase, Liver (PFKL) (AA 371-399) antibodyPFKL 适用: 人 WB 宿主: 兔 Polyclonal RB6851 unconjugated
anti-Phosphofructokinase, Liver (PFKL) (C-Term) antibodyPFKL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphofructokinase, Liver (PFKL) (AA 441-540) antibodyPFKL 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A9 unconjugated
anti-Phosphofructokinase, Liver (PFKL) (AA 669-699), (C-Term) antibodyPFKL 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB03903 unconjugated
anti-Phosphofructokinase, Liver (PFKL) (AA 1-827) antibodyPFKL 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- PFKL (Phosphofructokinase, Liver (PFKL))
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别名
- PFKL
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背景
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Description: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (PubMed:22923583). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway (By similarity).
Gene: PFKL
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分子量
- 85 kDa
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基因ID
- 5211
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UniProt
- P17858
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途径
- Negative Regulation of Hormone Secretion, Warburg Effect
抗原
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