MOBKL1A 抗体 (N-Term)
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北京 101111
Quick Overview for MOBKL1A 抗体 (N-Term) (ABIN6257009)
抗原
See all MOBKL1A (MOB1B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- MOB1A Antibody detects endogenous levels of total MOB1A.
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预测反应
- Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human MOB1A, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-MOB Kinase Activator 1B (MOB1B) (AA 2-216) antibody
MOB1B 适用: 人 ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (AA 177-206), (C-Term) antibodyMOB1B 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB12538 unconjugated
anti-MOB Kinase Activator 1B (MOB1B) antibodyMOB1B 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 3G9 unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (AA 120-216) antibodyMOB1B 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2F8 unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (AA 101-150) antibodyMOB1B 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (C-Term) antibodyMOB1B 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (Center) antibodyMOB1B 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))
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别名
- MOB1B
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背景
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Description: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L.
Gene: MOB1B
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分子量
- 25 kDa
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基因ID
- 92597
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UniProt
- Q7L9L4
抗原
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