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APOBEC3B 抗体 (N-Term)

APOBEC3B 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6256991
发货至: 中国
  • 抗原 See all APOBEC3B 抗体
    APOBEC3B (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B))
    抗原表位
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 20
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 18
    • 2
    克隆类型
    • 20
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    This APOBEC3B antibody is un-conjugated
    应用范围
    • 20
    • 12
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    APOBEC3D/F Antibody detects endogenous levels of total APOBEC3D/F.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human APOBEC3D/F, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    APOBEC3B (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B))
    别名
    APOBEC3D,APOBEC3F (APOBEC3B 产品)
    别名
    A3B antibody, APOBEC1L antibody, ARCD3 antibody, ARP4 antibody, DJ742C19.2 antibody, PHRBNL antibody, bK150C2.2 antibody, APOBEC3B antibody, Apobec3 antibody, Apobec3f antibody, APOBEC3F antibody, APOBEC3Z2 antibody, APOBEC3Z3 antibody, apolipoprotein B mRNA editing enzyme catalytic subunit 3B antibody, APOBEC3B antibody, Apobec3b antibody
    背景

    Description: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons.

    Gene: APOBEC3D

    分子量
    40 kDa
    基因ID
    200316
    UniProt
    Q96AK3, Q8IUX4
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