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BRMS1 抗体 (N-Term)

This anti-BRMS1 antibody is a 兔 多克隆 antibody detecting BRMS1 in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6256973
发货至: 中国

Quick Overview for BRMS1 抗体 (N-Term) (ABIN6256973)

抗原

See all BRMS1 抗体
BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

适用

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  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 48
  • 2

克隆类型

  • 46
  • 4
多克隆

标记

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  • 2
  • 2
  • 2
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This BRMS1 antibody is un-conjugated

应用范围

  • 43
  • 16
  • 13
  • 13
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    BRMS1 Antibody detects endogenous levels of total BRMS1.

    预测反应

    Pig,Horse,Sheep,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human BRMS1, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

    别名

    BRMS1

    背景

    Description: Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.

    Gene: BRMS1

    分子量

    28 kDa

    基因ID

    25855

    UniProt

    Q9HCU9
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