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Coxsackie Adenovirus Receptor 抗体 (N-Term)

This anti-Coxsackie Adenovirus Receptor antibody is a 兔 多克隆 antibody detecting Coxsackie Adenovirus Receptor in WB, ELISA, ICC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6256932
发货至: 中国
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Quick Overview for Coxsackie Adenovirus Receptor 抗体 (N-Term) (ABIN6256932)

抗原

See all Coxsackie Adenovirus Receptor (CXADR) 抗体
Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

适用

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人, 小鼠, 大鼠

宿主

  • 43
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克隆类型

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多克隆

标记

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This Coxsackie Adenovirus Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

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    N-Term

    特异性

    CXADR Antibody detects endogenous levels of total CXADR.

    预测反应

    Pig,Bovine,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human CXADR, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

    别名

    CXADR

    背景

    Description: Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

    Gene: CXADR

    分子量

    40 kDa

    基因ID

    1525

    UniProt

    P78310

    途径

    Cell-Cell Junction Organization
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